Drugs: From Discovery to Approval by Rick Ng

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The third edition of this best-selling book continues to offer a user-friendly, step-by-step introduction to all the key processes involved in bringing a drug to the market, including the performance of pre-clinical studies, the conduct of human clinical trials, regulatory controls, and even the manufacturing processes for pharmaceutical products. 

Concise and easy to read, Drugs: From Discovery to Approval, Third Edition quickly introduces basic concepts, then moves on to discuss target selection and the drug discovery process for both small and large molecular drugs. The third edition incorporates the latest developments and updates in the pharmaceutical community, provides more comprehensive coverage of topics, and includes more materials and case studies suited to college and university use. Biotechnology is a dynamic field with changes across R&D, clinical trials, manufacturing and regulatory processes, and the third edition of the text provides timely updates for those in this rapidly growing field.

From reader reviews:

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Pamela Wilson:

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Tex mensuel, Tomes 444-445-446 :

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From reader reviews:

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Draw Cars : Learn To Draw Cars For Beginners: Pencil Drawing Cars Step By Step Guide Book (How to Draw : Drawing Lessons for Beginners) by Gala Studio

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Learn to Draw Cars: Pencil Drawings Step by Step Easy steps and you can draw! Start with basic Cars sketches and you will be drawing wonderful pictures in no time! The step by step drawings give you room to practice your drawing talent. Many different Cars are there for you to try – you can even color the finished drawings if you like! Ideal for ages 3 to 11 years, preschool to grade 5.

From reader reviews:

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Lords of EverQuest (Prima's Official Strategy Guide) by Elliott Chin, Ron Dulin

Lords of EverQuest (Prima's Official Strategy Guide) by Elliott Chin, Ron Dulin PDF, ePub eBook D0wnl0ad

Let the battle for Antonica begin!
·Strategies for playing all three factions
·Tips on every unit in the game
·Details on all special abilities and spells for every lord, knight, and unit
·Maps for all single- and multiplayer quests
·Complete walkthroughs for all 36 missions!

From reader reviews:

Travis Wysocki:

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Susan Gagnon:

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James Hibner:

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Elasticity: Tensor, Dyadic, and Engineering Approaches (Dover Civil and Mechanical Engineering) by Pei Chi Chou, Nicholas J. Pagano

Elasticity: Tensor, Dyadic, and Engineering Approaches (Dover Civil and Mechanical Engineering) by Pei Chi Chou, Nicholas J. Pagano PDF, ePub eBook D0wnl0ad

Written for advanced undergraduates and beginning graduate students, this exceptionally clear text treats both the engineering and mathematical aspects of elasticity. It is especially useful because it offers the theory of linear elasticity from three standpoints: engineering, Cartesian tensor, and vector-dyadic. In this way the student receives a more complete picture and a more thorough understanding of engineering elasticity. Prerequisites are a working knowledge of statics and strength of materials plus calculus and vector analysis.
The first part of the book treats the theory of elasticity by the most elementary approach, emphasizing physical significance and using engineering notations. It gives engineering students a clear, basic understanding of linear elasticity. The latter part of the text, after Cartesian tensor and dyadic notations are introduced, gives a more general treatment of elasticity. Most of the equations of the earlier chapters are repeated in Cartesian tensor notation and again in vector-dyadic notation. By having access to this threefold approach in one book, beginning students will benefit from cross-referencing, which makes the learning process easier.
Another helpful feature of this text is the charts and tables showing the logical relationships among the equations — especially useful in elasticity, where the mathematical chain from definition and concept to application is often long. Understanding of the theory is further reinforced by extensive problems at the end of each chapter.

From reader reviews:

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Management and Welfare of Farm Animals: The UFAW Farm Handbook

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Through successive editions, Management and Welfare of Farm Animals has gained international recognition as a classic introductory textbook for students of agriculture and veterinary science. Conceived by the Universities Federation for Animal Welfare (UFAW), the book has always sought to promote the humane treatment of livestock within the practical business context of modern farming.

Now fully revised and updated, this fifth edition remains the most comprehensive and accessible guide available. Three animal groups appear here for the first time (game birds, South American camelids, and ostriches), and a chapter on horses has also been restored. Throughout, the book offers clear advice for the humane management of all major farmed species in the primary context of large-scale food production.

However, this edition also takes full account of consumer demand (and legal requirements) for alternative farming methods and enhanced welfare standards, whether in conventional agriculture or the smallest of ‘hobby' farms. Brand new chapters reflect fresh understanding of welfare science, ethics, and the role of society in ensuring the best possible farm conditions. It remains an indispensable resource for students, and for all those seeking to promote animal welfare.

Published as a part of the prestigious Wiley-Blackwell – UFAW Animal Welfare series. UFAW, founded 1926, is an internationally recognised, independent, scientific and educational animal welfare charity. For full details of all titles available in the UFAW series, please visit www.wiley.com/go/ufaw.

From reader reviews:

Richard Smith:

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James Ray:

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Carmen Fantasy and Other Concert Favorites for Violin and Piano: With Separate Violin Part by Pablo de Sarasate

Carmen Fantasy and Other Concert Favorites for Violin and Piano: With Separate Violin Part by Pablo de Sarasate PDF, ePub eBook D0wnl0ad

These classics by one of the 19th century’s great violinists represent a selection unavailable elsewhere. In addition to the title work, this volume features the well-known Zigeunerweisen (Gypsy Airs), plus Habanera, Romanza andaluza, Jota navarra, Playera, Zapateado, and El canto del ruiseñor.

From reader reviews:

Tonya Deschamps:

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Teresa Vanhook:

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Michael Kautz:

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The Shallows: What the Internet Is Doing to Our Brains by Nicholas Carr

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Finalist for the 2011 Pulitzer Prize in General Nonfiction: “Nicholas Carr has written a Silent Spring for the literary mind.”―Michael Agger, Slate

“Is Google making us stupid?” When Nicholas Carr posed that question, in a celebrated Atlantic Monthly cover story, he tapped into a well of anxiety about how the Internet is changing us. He also crystallized one of the most important debates of our time: As we enjoy the Net’s bounties, are we sacrificing our ability to read and think deeply?

Now, Carr expands his argument into the most compelling exploration of the Internet’s intellectual and cultural consequences yet published. As he describes how human thought has been shaped through the centuries by “tools of the mind”―from the alphabet to maps, to the printing press, the clock, and the computer―Carr interweaves a fascinating account of recent discoveries in neuroscience by such pioneers as Michael Merzenich and Eric Kandel. Our brains, the historical and scientific evidence reveals, change in response to our experiences. The technologies we use to find, store, and share information can literally reroute our neural pathways.

Building on the insights of thinkers from Plato to McLuhan, Carr makes a convincing case that every information technology carries an intellectual ethic―a set of assumptions about the nature of knowledge and intelligence. He explains how the printed book served to focus our attention, promoting deep and creative thought. In stark contrast, the Internet encourages the rapid, distracted sampling of small bits of information from many sources. Its ethic is that of the industrialist, an ethic of speed and efficiency, of optimized production and consumption―and now the Net is remaking us in its own image. We are becoming ever more adept at scanning and skimming, but what we are losing is our capacity for concentration, contemplation, and reflection.

Part intellectual history, part popular science, and part cultural criticism, The Shallows sparkles with memorable vignettes―Friedrich Nietzsche wrestling with a typewriter, Sigmund Freud dissecting the brains of sea creatures, Nathaniel Hawthorne contemplating the thunderous approach of a steam locomotive―even as it plumbs profound questions about the state of our modern psyche. This is a book that will forever alter the way we think about media and our minds.

From reader reviews:

Donald Perkins:

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Mary Larrick:

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Frog (Life Cycle of A...) by Angela Royston

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This is one in a series of books that takes an in-depth look at the life cycles of familiar plants and animals. This text looks at the frog and aims to give an understanding that animals move, feed, grow, use their senses and reproduce. The stages of development are explained through simple text and photography, and an illustrated timeline on each page charts these stages within the lifespan of the frog. Other features include "see for yourself" activities and "did you know?" panels containing facts and records. The author specializes in zoology and human biology for younger readers.

From reader reviews:

Robert Russo:

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Pedro Turk:

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Domingo Adams:

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Cardiac Catheterization for Congenital Heart Disease: From Fetal Life to Adulthood

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This handbook is an ideal, up-to-date guide to the application of catheter-based interventions across the entire patient age range, from fetal life through to adulthood. Clear instruction is offered on techniques of vascular access, valve dilatation, angioplasty, stent implantation, defect closure, defect creation, pulmonary valve implantation and the hybrid approach, as well as miscellaneous other procedures. Topics are approached using a step-by-step format, ensuring that the reader will immediately be able to access information relevant to daily practice. Many explanatory figures and drawings are included in each chapter in order to clarify further how to plan, perform and evaluate diagnostic and interventional procedures in the field of congenital heart disease. Attention is drawn to important tips and tricks that will assist in achieving optimal outcomes and an appendix includes additional general equations and BSA and oxygen consumption charts.

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Succeeding with Agile: Software Development Using Scrum by Mike Cohn

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Proven, 100% Practical Guidance for Making Scrum and Agile Work in Any Organization

 

This is the definitive, realistic, actionable guide to starting fast with Scrum and agile–and then succeeding over the long haul. Leading agile consultant and practitioner Mike Cohn presents detailed recommendations, powerful tips, and real-world case studies drawn from his unparalleled experience helping hundreds of software organizations make Scrum and agile work.

 

Succeeding with Agile is for pragmatic software professionals who want real answers to the most difficult challenges they face in implementing Scrum. Cohn covers every facet of the transition: getting started, helping individuals transition to new roles, structuring teams, scaling up, working with a distributed team, and finally, implementing effective metrics and continuous improvement.

 

Throughout, Cohn presents “Things to Try Now” sections based on his most successful advice. Complementary “Objection” sections reproduce typical conversations with those resisting change and offer practical guidance for addressing their concerns. Coverage includes 

• Practical ways to get started immediately–and “get good” fast
• Overcoming individual resistance to the changes Scrum requires
• Staffing Scrum projects and building effective teams
• Establishing “improvement communities” of people who are passionate about driving change
• Choosing which agile technical practices to use or experiment with
• Leading self-organizing teams
• Making the most of Scrum sprints, planning, and quality techniques
• Scaling Scrum to distributed, multiteam projects
• Using Scrum on projects with complex sequential processes or challenging compliance and governance requirements
• Understanding Scrum’s impact on HR, facilities, and project management

Whether you've completed a few sprints or multiple agile projects and whatever your role–manager, developer, coach, ScrumMaster, product owner, analyst, team lead, or project lead–this book will help you succeed with your very next project. Then, it will help you go much further: It will help you transform your entire development organization.

 

From reader reviews:

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Hands-On Start to Wolfram Mathematica: and Programming with the Wolfram Language by Cliff Hastings, Kelvin Mischo, Michael Morrison

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For more than 25 years, Mathematica has been the principal computation environment for millions of innovators, educators, students, and others around the world. This book is an introduction to Mathematica. The goal is to provide a hands-on experience introducing the breadth of Mathematica, with a focus on ease of use. Readers get detailed instruction with examples for interactive learning and end-of-chapter exercises. Each chapter also contains authors tips from their combined 50+ years of Mathematica use.

From reader reviews:

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Bruce Lee. El arte de expresarse con el cuerpo (Spanish Edition) by Bruce Lee

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Durante décadas muchas personas se han preguntado cómo Bruce Lee consiguió moldear su cuerpo y, por extensión, su excelente forma física. Este libro da las respuestas de la mano del propio Lee. A través de sus escritos, cartas, diarios, entrevistas y fotografías, el lector se adentrará en su manera de entrenar y en su propia filosofía, de manera que podrá aplicar estos conocimientos a su desarrollo personal.

From reader reviews:

Joshua Orvis:

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Learning and Behavior: Seventh Edition by James E. Mazur

Learning and Behavior: Seventh Edition by James E. Mazur PDF, ePub eBook D0wnl0ad

A thorough survey of the field of learning.

Learning & Behavior covers topics such as classical and operant conditioning, reinforcement schedules, avoidance and punishment, stimulus control, comparative cognition, observational learning, motor skill learning, and choice.

The book includes thorough coverage of classic studies and the most recent developments and trends, while providing examples of real-world applications of the principles discovered in laboratory research. It also emphasizes the behavioral approach but not exclusively so; many cognitive theories are covered as well, and there is a chapter on comparative cognition.

Learning Goals

Upon completing this book readers will be able to:

• Understand the field of learning
• Discuss real-world applications of learning principles

From reader reviews:

Lawrence Seay:

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Essence of Creativity: A Guide to Tackling Difficult Problems by Steven Kim

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Challenging problems both attract and repel us. They frustrate us, accelerate our pulses, cause ulcers, and perhaps even curtail our lifespans. On the other hand, the knotty problems of life offer us food for thought, sustaining our creativity, and adding emotional spice to the human experience. We encounter difficult tasks day in and day out. The solutions to these problems must be sought with resourcefulness and creativity, for until now we have had little insight into the nature of these tasks, and even less into methods for resolving them. This unique book explores the nature of challenging problems in all walks of life, and describes the creative techniques for addressing them. It is particularly relevant for problems that admit no obvious solution, whether they concern scientific knowledge, technology, the arts, or social situations. By understanding the dynamics of problem solving in general, the author argues, we can better organize the pursuit of specific projects. The initial phase involves crystallizing our objectives and developing a coherent plan. The next step is to evaluate the results and determine whether the work should be concluded, begun anew, or given up altogether. With this general strategy, even seemingly overwhelming problems can be approached systematically and efficiently. The author goes beyond the normal distinction between routine and innovative activities, defining the role of creativity in novel decision-making. In addition, he distills the existing literature on creativity, innovation, and project management to present a concise set of strategies and practices that can be applied in a myriad of settings ranging from university laboratories to corporate planning centers. For the sake of concreteness, a number of examples from research and development environments demonstrate the book's basic principles in action, showing how even the most difficult problems can yield to knowledgeable ingenuity. Written in a clear, readable style, Essence of Creativity will appeal to a broad spectrum of readers: engineers, business managers, computer scientists, executives, cognitive psychologists, and educators in many fields, as well as general readers seeking effective ways to handle difficult problems.

From reader reviews:

Alice Smith:

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Diagnosis and Management of Ocular Motility Disorders by Alec M. Ansons, Helen Davis

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As in previous editions, the aim of the third edition of this book is to provide guidance on the diagnosis and management of ocular motility disorders which is based on clinical experience. This edition sees a new team of authors who have kept very much to this principle in their nevertheless thorough revision of the book. All chapters have been comprehensively revised and updated and a new chapter on an 'Introduction to concomitant strabismus' has been added. The immediate impact of this extensive revision can be seen in the improved page layout with increased use of diagrams and tables. There are also new sections on feigned visual loss in adults and children, and the management of residual defects, whilst the section on botulinum toxin treatment has been completely rewritten to take account of the great advances in this form of treatment.

From reader reviews:

Ramona Wegener:

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Q Solutions: Essential Resources for the Healthcare Quality Professional by Luc R. Pelletier and Christy Beaudin

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Q Solutions: Essential Resources for the Healthcare Quality Professional, servies as the resource for healthcare quality professionals, including those seeking certification as a Certified Professional in Healthcare Quality (CPHQ). The second edition includes a fifth module on healthcare safety culture to correspond with the addition of patient safety to the CPHQ certification exam. Modules 1-4 have also been updated to reflect recent changes in national healthcare safety initiatives.

From reader reviews:

Janice Perry:

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